During her doctoral studies, our research team member, Tzu-Yu Lai, has demonstrated outstanding performance, rigorous academic training, and exceptional research capabilities, along with the potential for interdisciplinary integration. Her research findings have been officially published in the top-tier international cardiovascular medical journal European Heart Journal, titled “Association of radiation dose to cardiac substructures with major ischaemic events following breast cancer radiotherapy”, in Volume 44, Issue 45, published on December 1, 2023.
This study focuses on the association between radiation doses to cardiac substructures and major ischaemic cardiovascular events following breast cancer radiotherapy. By retrospectively analyzing 2,158 breast cancer patients who underwent postoperative radiotherapy, the study further explores the predictive value of various cardiac dose parameters for clinical events. The results indicate that in left-sided breast cancer patients, a left ventricular volume receiving 25 Gy or more of at least 4% (LV V25 ≥ 4%) may be a better predictor than the mean heart dose, holding significant clinical implications for future cardiac-sparing strategies in radiotherapy.
Completing such clinically significant and academically influential research during her doctoral training, and having it published in a major international journal, is truly commendable. It fully demonstrates Dr. Tzu-Yu Lai’s profound expertise in research design, data analysis, and academic writing. This achievement is not only a concrete manifestation of her personal effort and perseverance but also represents a continuous advancement and a significant milestone for our research team in the integrated study of clinical medicine, radiotherapy, epidemiology, and data science.
We extend our sincere congratulations and thank all team members who participated in this study for their dedicated efforts. We look forward to Dr. Lai’s continued success and further contributions to the fields of academic research and professional development.
Reference: https://pubmed.ncbi.nlm.nih.gov/37585426/